JH-II-127 | Tocris Bioscience 6289 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

JH-II-127

catalog :

6289

quantity :

10 mg (also 50 mg)

price :

208 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

6289

SKU :

6289/10

product name :

JH-II-127

description :

Potent and selective LRRK2 inhibitor

target :

LRRK2 Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

416.87

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent and selective LRRK2 inhibitor (IC50 values are 2.2, 6.6 and 47.7 nM for G2019S-mutant, wild-type and A2016T-mutant LRRK2, respectively). Selective for LRRK2 over a panel of 138 kinases. Brain penetrant and orally bioavailable.

catalog number base :

6289

product keywords :

potent selective Leucine-rich repeat kinase 2 LRRK2 inhibitor inhibits orally bioavaillable brain penetrant Parkinson's parkinsons LRRK2 6289, LRRK 2

extended description :

Potent and selective LRRK2 inhibitor

chemical name text :

[4-[[5-Chloro-4-(methylamino)-7H-pyrrolo[2,3-d]pyrimidin-2-yl]amino]-3-methoxyphenyl]-4-morpholinyl-methanone

formula :

C 19 H 21 ClN 6 O 3

formula text :

C19H21ClN6O3

cas num :

1700693-08-8

2020 USD :

203

2021 USD :

208 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage