6289/10 | Tocris Bioscience 6289/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

6289/10

catalog :

6289/10

quantity :

10 mg (also 50 mg)

price :

233 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 6289 - JH-II-127 C19H21ClN6O3 CAS No. 1700693-08-8

product information

master code :

6289

SKU :

6289/10

product name :

JH-II-127

unit size :

10 mg (also 50 mg)

description :

Potent and selective LRRK2 inhibitor

target :

LRRK2 Inhibitors

category :

Small Molecules

purity :

98%

observed molecular weight :

416.87

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

JH-II-127 is a potent and selective LRRK2 inhibitor (IC50 values are 2.2, 6.6 and 47.7 nM for G2019S-mutant, wild-type and A2016T-mutant LRRK2, respectively). Selective for LRRK2 over a panel of 138 kinases. Brain penetrant and orally bioavailable.

top caption :

Potent and selective LRRK2 inhibitor

extended description :

Potent and selective LRRK2 inhibitor

chemical name text :

[4-[[5-Chloro-4-(methylamino)-7H-pyrrolo[2,3-d]pyrimidin-2-yl]amino]-3-methoxyphenyl]-4-morpholinyl-methanone

formula :

C19H21ClN6O3

formula text :

C19H21ClN6O3

cas num :

1700693-08-8

USD :

233 USD

product details :

Potent and selective LRRK2 inhibitor

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage