JNJ 39758979 dihydrochloride | Tocris Bioscience 6279 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

JNJ 39758979 dihydrochloride

catalog :

6279

quantity :

25 mg

price :

343 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

6279

SKU :

6279/25

product name :

JNJ 39758979 dihydrochloride

description :

High affinity and selective histamine H4 antagonist; orally bioavailable

target :

Histamine H4 Receptor Antagonists

category :

Small Molecules

unit size :

25 mg

purity :

98%

observed molecular weight :

294.22

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

High affinity and selective histamine H4 antagonist (Ki = 12.5 nM). Exhibits 80-fold selectivity for H4 over other histamine receptors and no significant activity at a range of other targets. Inhibits histamine-induced eosinophil shape change in whole blood in vitro and ovalbumin-induced inflammation in ovalbumin-sensitized mice in vivo . Orally bioavailable.

catalog number base :

6279

product keywords :

JNJ39758979 2HCl 1046447-90-8 high affinity selective histamine H4 antagonists antagonism anti-inflammatory orally bioavailable Histamine H4 Receptors 6279,

extended description :

High affinity and selective histamine H4 antagonist; orally bioavailable

chemical name text :

4-[(3R)-3-Amino-1-pyrrolidinyl]-6-(1-methylethyl)-2-pyridinamine dihydrochloride

formula :

C 11 H 19 N 5 .2HCl

formula text :

C11H19N5.2HCl

2020 USD :

329

2021 USD :

343 USD

storage :

Desiccate at RT

more info or order :

Tocris Bioscience product webpage