JNJ 55511118 | Tocris Bioscience 6278 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

JNJ 55511118

catalog :

6278

quantity :

25 mg

price :

360 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

6278

SKU :

6278/25

product name :

JNJ 55511118

description :

High affinity and selective negative modulator of AMPA receptors containing TARP- 8

target :

AMPA Receptor Modulators

category :

Small Molecules

unit size :

25 mg

purity :

98%

observed molecular weight :

328.67

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

High affinity and selective negative modulator of AMPA receptors containing TARP- 8 (Ki = 26 nM). Exhibits 50% binding against a panel of 52 receptors, ion channels and transporters (except 5HT2B and melatonin receptors 78% and 57%, respectively). Also displays minimal activity against other TARP-less AMPARs and AMPARs coexpressed with other TARPs or CNIH2. Orally bioavailable and brain penetrant. Anticonvulsant.

catalog number base :

6278

product keywords :

JNJ55511118 High affinity selective negative modulators modulates AMPA receptors containing TARP-gamma8 TARP- 8 AMPA Receptors 6278,

extended description :

High affinity and selective negative modulator of AMPA receptors containing TARP- 8

chemical name text :

5-[2-Chloro-6-(trifluoromethoxy)phenyl]-1,3-dihydro-2H-benzimidazol-2-one

formula :

C 14 H 8 ClF 3 N 2 O 2

formula text :

C14H8ClF3N2O2

cas num :

2036081-86-2

2020 USD :

349

2021 USD :

360 USD

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage