product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
ST 034307
catalog :
6271
quantity :
10 mg (also 50 mg)
price :
141 USD
more info or order :
citations: 1
Reference
Cheng Y, Huang P, Meng B, Gan L, Wu D, Cao Y. Antinociceptive effects of the adenylyl cyclase inhibitor ST034307 on tooth-movement-induced nociception in rats. Arch Oral Biol. 2019;98:81-86 pubmed publisher
product information
brand :
Tocris
master code :
6271
SKU :
6271/10
product name :
ST 034307
description :
Adenylyl cyclase 1 (AC1) inhibitor; analgesic and active in vivo
target :
Adenylyl Cyclase Inhibitors
category :
Small Molecules
unit size :
10 mg (also 50 mg)
purity :
98%
observed molecular weight :
297.95
url print :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Adenylyl cyclase 1 (AC1) inhibitor (IC50 = 2.3 M). Exhibits some selectivity for AC1 over other AC isoforms, with no significant activity against AC8. Inhibits Ca2+/calmodulin-stimulated cAMP accumulation in hippocampal homogenates. Enhances opioid receptor (MOR)-mediated inhibition of AC1 in cellular assays and inhibits development and maintenance of MOR-mediated sensitization of AC1. Active in vivo . Analgesic.
catalog number base :
6271
product keywords :
ST034307 adenylyl cyclase inhibitors inhibits AC1 active in vivo analgesic cAMP Adenylyl Cyclase 6271,
extended description :
Adenylyl cyclase 1 (AC1) inhibitor; analgesic and active in vivo
chemical name text :
6-Chloro-2-(trichloromethyl)-4H-1-benzopyran-4-one
formula :
C 10 H 4 Cl 4 O 2
formula text :
C10H4Cl4O2
cas num :
133406-29-8
2020 USD :
135
2021 USD :
141 USD
storage :
Store at -20°C
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK