product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
Tubastatin A hydrochloride
catalog :
6270
quantity :
10 mg
price :
126 USD
more info or order :
product information
brand :
Tocris
master code :
6270
SKU :
6270/10
product name :
Tubastatin A hydrochloride
description :
Potent HDAC6 inhibitor
target :
Class II Histone Deacetylases Inhibitors
category :
Small Molecules
unit size :
10 mg
purity :
98%
observed molecular weight :
371.86
url print :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Potent HDAC6 inhibitor (IC50 = 0.015 M). Exhibits some selectively for HDAC6 over HDAC8 and 1 (IC50 values are 0.854 and 16.4 M, respectively). Induces elevated levels of -tubulin and protects against glutathione-induced oxidative stress in primary neuronal cell culture. Reverses the axonal loss in peripheral neurons in a mouse model of Charcot-Marie-Tooth disease.
catalog number base :
6270
product keywords :
HDAC6 potent inhibitors inhibits histone deacetylases Class II HDACs 6270,
extended description :
Potent HDAC6 inhibitor
chemical name text :
N-Hydroxy-4-[(1,2,3,4-tetrahydro-2-methyl-5H-pyrido[4,3-b]indol-5-yl)methyl]benzamide hydrochloride
formula :
C 20 H 21 N 3 O 2 .HCl
formula text :
C20H21N3O2.HCl
cas num :
1310693-92-5
2020 USD :
123
2021 USD :
126 USD
storage :
Store at -20°C
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK