6270/10 | Tocris Bioscience 6270/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

6270/10

catalog :

6270/10

quantity :

10 mg

price :

159 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Calabrese B, Jones S, Shiraishi Yamaguchi Y, Lingelbach M, Manor U, Svitkina T, et al. INF2-mediated actin filament reorganization confers intrinsic resilience to neuronal ischemic injury. Nat Commun. 2022;13:6037 pubmed publisher

image

image 1 :

Cat.No. 6270 - Tubastatin A hydrochloride C20H21N3O2.HCl CAS No. 1310693-92-5

product information

master code :

6270

SKU :

6270/10

product name :

Tubastatin A hydrochloride

unit size :

10 mg

description :

Potent HDAC6 inhibitor

target :

Class II Histone Deacetylases Inhibitors

category :

Small Molecules

purity :

98%

observed molecular weight :

371.86

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Tubastatin A hydrochloride is a potent HDAC6 inhibitor (IC50 = 0.015 M). Exhibits some selectively for HDAC6 over HDAC8 and 1 (IC50 values are 0.854 and 16.4 M, respectively). Induces elevated levels of -tubulin and protects against glutathione-induced oxidative stress in primary neuronal cell culture. Reverses the axonal loss in peripheral neurons in a mouse model of Charcot-Marie-Tooth disease.

top caption :

Potent HDAC6 inhibitor

extended description :

Potent HDAC6 inhibitor

chemical name text :

N-Hydroxy-4-[(1,2,3,4-tetrahydro-2-methyl-5H-pyrido[4,3-b]indol-5-yl)methyl]benzamide hydrochloride

formula :

C20H21N3O2.HCl

formula text :

C20H21N3O2.HCl

cas num :

1310693-92-5

USD :

159 USD

product details :

Potent HDAC6 inhibitor

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage