product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
6269/5
catalog :
6269/5
quantity :
5 mg (also 25 mg)
price :
105 USD
more info or order :
citations: 2
Reference
Plumbly W, Patikas N, Field S, Foskolou S, Metzakopian E. Derivation of nociceptive sensory neurons from hiPSCs with early patterning and temporally controlled NEUROG2 overexpression. Cell Rep Methods. 2022;2:100341 pubmed publisher
Takaya J, Mio K, Shiraishi T, Kurokawa T, Otsuka S, Mori Y, et al. A Potent and Site-Selective Agonist of TRPA1. J Am Chem Soc. 2015;137:15859-64 pubmed publisher
image
image 1 :
Tocris Bioscience 6269/5 image 1
Cat.No. 6269 - JT010 C16H19ClN2O3S CAS No. 917562-33-5
product information
master code :
6269
SKU :
6269/5
product name :
JT010
unit size :
5 mg (also 25 mg)
description :
Potent and selective TRPA1 channel activator
target :
TRPA1 Activators
category :
Small Molecules
purity :
98%
observed molecular weight :
354.85
url print :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
JT010 is a potent and selective TRPA1 channel activator (EC50 = 0.65 nM); activates the TRPA1 channel by covalently and site-selectively binding to Cys621. Exhibits selectivity for TRPA1 over TRPV1, TRPV3, TRPV4, TRPM2, TRPM8, and TRPC5 channels (EC50 values are 1 M).
top caption :
Potent and selective TRPA1 channel activator
extended description :
Potent and selective TRPA1 channel activator
chemical name text :
2-Chloro-N-[4-(4-methoxyphenyl)-2-thiazolyl]-N-(3-methoxypropyl)acetamide
formula :
C16H19ClN2O3S
formula text :
C16H19ClN2O3S
cas num :
917562-33-5
USD :
105 USD
product details :
Potent and selective TRPA1 channel activator
storage :
Store at +4░C
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK