product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
Tocriscreen Kinase Inhibitor Library
catalog :
6268
quantity :
1 Set
price :
3995 USD
more info or order :
citations: 11
Reference
Sherman H, Rossi A. A Novel Three-Dimensional Glioma Blood-Brain Barrier Model for High-Throughput Testing of Tumoricidal Capability. Front Oncol. 2019;9:351 pubmed publisher
Yang X, Shen H, Buckley B, Chen Y, Yang N, Mussell A, et al. NTRK1 is a positive regulator of YAP oncogenic function. Oncogene. 2019;38:2778-2787 pubmed publisher
Chaudhari P, Tian L, Kim A, Zhu Q, Anders R, Schwarz K, et al. Transient c-Src Suppression During Endodermal Commitment of Human Induced Pluripotent Stem Cells Results in Abnormal Profibrotic Cholangiocyte-Like Cells. Stem Cells. 2019;37:306-317 pubmed publisher
Moeschler S, Locher S, Zimmer G. 1-Benzyl-3-cetyl-2-methylimidazolium Iodide (NH125) Is a Broad-Spectrum Inhibitor of Virus Entry with Lysosomotropic Features. Viruses. 2018;10: pubmed publisher
Azad T, Janse van Rensburg H, Lightbody E, Neveu B, Champagne A, Ghaffari A, et al. A LATS biosensor screen identifies VEGFR as a regulator of the Hippo pathway in angiogenesis. Nat Commun. 2018;9:1061 pubmed publisher
Markussen L, Winther S, Wicksteed B, Hansen J. GSK3 is a negative regulator of the thermogenic program in brown adipocytes. Sci Rep. 2018;8:3469 pubmed publisher
Sandilands E, Schoenherr C, Frame M. p70S6K is regulated by focal adhesion kinase and is required for Src-selective autophagy. Cell Signal. 2015;27:1816-23 pubmed publisher
Tandon M, Salamoun J, Carder E, Farber E, Xu S, Deng F, et al. SD-208, a novel protein kinase D inhibitor, blocks prostate cancer cell proliferation and tumor growth in vivo by inducing G2/M cell cycle arrest. PLoS ONE. 2015;10:e0119346 pubmed publisher
FitzGerald J, Murillo L, O Brien G, O Connell E, O Connor A, Wu K, et al. A high through-put screen for small molecules modulating MCM2 phosphorylation identifies Ryuvidine as an inducer of the DNA damage response. PLoS ONE. 2014;9:e98891 pubmed publisher
Acevedo K, Opazo C, Norrish D, Challis L, Li Q, White A, et al. Phosphorylation of amyloid precursor protein at threonine 668 is essential for its copper-responsive trafficking in SH-SY5Y neuroblastoma cells. J Biol Chem. 2014;289:11007-19 pubmed publisher
Moujalled D, James J, Parker S, Lidgerwood G, Duncan C, Meyerowitz J, et al. Kinase Inhibitor Screening Identifies Cyclin-Dependent Kinases and Glycogen Synthase Kinase 3 as Potential Modulators of TDP-43 Cytosolic Accumulation during Cell Stress. PLoS ONE. 2013;8:e67433 pubmed publisher
product information
brand :
Tocris
master code :
6268
SKU :
6268/1 SET
product name :
Tocriscreen Kinase Inhibitor Library
description :
A bioactive compound library of 160 kinase inhibitors (250 L 10 mM DMSO solutions) for high-throughput screening, high-content screening and chemical biology applications
target :
Screening Libraries
category :
Small Molecules
unit size :
1 Set
url print :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
A collection of 160 kinase inhibitors supplied pre-dissolved in DMSO (250 L 10 mM solution). The Tocriscreen Kinase Inhibitor Library contains compounds targeting 60 different kinases, including extensive coverage of well-established targets such as VEFGR, AKT and TGF R as well as more novel targets such as LIMK, Hapsin, NUAK1 and DYRK. . If this library does not suit your needs, please submit your requirements through our Tocriscreen PRO custom compound library service .
catalog number base :
6268
product keywords :
tocriscreen kinase inhibitor library kinases toolbox inhibitors inhibits compound libraries Tocriscreen Compound Libraries 6268, Screening Libraries
extended description :
A bioactive compound library of 160 kinase inhibitors (250 L 10 mM DMSO solutions) for high-throughput screening, high-content screening and chemical biology applications
2020 USD :
3995
2021 USD :
3995 USD
storage :
Store at -20°C
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK