product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
6259/1
catalog :
6259/1
quantity :
1 mg
price :
123 USD
more info or order :
citations: 4
Reference
Thom S, Bhopale V, Arya A, Ruhela D, Bhat A, Mitra N, et al. Blood-Borne Microparticles Are an Inflammatory Stimulus in Type 2 Diabetes Mellitus. Immunohorizons. 2023;7:71-80 pubmed publisher
Hoste E, Maueröder C, Van Hove L, Catrysse L, Vikkula H, Sze M, et al. Epithelial HMGB1 Delays Skin Wound Healing and Drives Tumor Initiation by Priming Neutrophils for NET Formation. Cell Rep. 2019;29:2689-2701.e4 pubmed publisher
Uderhardt S, Martins A, Tsang J, Lämmermann T, Germain R. Resident Macrophages Cloak Tissue Microlesions to Prevent Neutrophil-Driven Inflammatory Damage. Cell. 2019;177:541-555.e17 pubmed publisher
Arumugam T, Ramachandran V, Gomez S, Schmidt A, Logsdon C. S100P-derived RAGE antagonistic peptide reduces tumor growth and metastasis. Clin Cancer Res. 2012;18:4356-64 pubmed publisher
product information
master code :
6259
SKU :
6259/1
product name :
RAGE antagonist peptide
unit size :
1 mg
description :
RAGE antagonist
target :
NFkB/IkB Inhibitors
category :
Peptides
purity :
95%
observed molecular weight :
1272.56
url print :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=peptides
details of functionality :
RAGE antagonist peptide is a receptor for advanced glycation end products (RAGE) antagonist. Blocks S100P, S100A4 and HMGB-1 mediated RAGE activation in vitro and in vivo . Inhibits growth and metastasis of rat glioma tumors. Reduces cell growth and RAGE-mediated NF- B activity in human PDAC cell lines. Inhibits effects of TDI exposure in BALB/c mice.
top caption :
RAGE antagonist
extended description :
RAGE antagonist
formula :
C57H101N13O17S
formula text :
C57H101N13O17S
cas num :
1092460-91-7
USD :
123 USD
product details :
RAGE antagonist
storage :
Store at -20░C
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK