Givinostat hydrochloride | Tocris Bioscience 6249 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Givinostat hydrochloride

catalog :

6249

quantity :

25 mg

price :

381 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

6249

SKU :

6249/25

product name :

Givinostat hydrochloride

description :

Histone deacetylase inhibitor

target :

Class I Histone Deacetylases Inhibitors

category :

Small Molecules

unit size :

25 mg

purity :

98%

observed molecular weight :

457.95

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Histone deacetylase (HDAC) inhibitor (IC50 = 7.5 to 16 nM). At low concentrations reduces release of pro-inflammatory cytokines, including TNF , INF , IL-1 and IL-1 , from LPS stimulated PBMCs in vitro . Exhibits anti-inflammatory effects in vivo . Improves functional recovery and attenuates tissue damage in a mouse model of traumatic brain injury.

catalog number base :

6249

product keywords :

HDAC histone deacetylase inhibitors inhibits ITF2357 Givinostat anti-inflammatory ITF 2357 Non-selective HDACs Non-Selective HDACs 6249,

extended description :

Histone deacetylase inhibitor

chemical name text :

[6-[(Diethylamino)methyl]-2-naphthalenyl]methyl-N-[4-[(hydroxyamino)carbonyl]phenyl]carbamate hydrochloride

formula :

C 24 H 27 N 3 O 4 .HCl

formula text :

C24H27N3O4.HCl

cas num :

199657-29-9

2020 USD :

369

2021 USD :

381 USD

alt names :

ITF 2357

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage