6249/5 | Tocris Bioscience 6249/5 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

6249/5

catalog :

6249/5

quantity :

5 mg (also 25 mg)

price :

124 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 6249 - Givinostat hydrochloride C24H27N3O4.HCl CAS No. 199657-29-9

product information

master code :

6249

SKU :

6249/5

product name :

Givinostat hydrochloride

unit size :

5 mg (also 25 mg)

description :

Histone deacetylase inhibitor

target :

Class I Histone Deacetylases Inhibitors

category :

Small Molecules

purity :

98%

observed molecular weight :

457.95

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Givinostat hydrochloride is a histone deacetylase (HDAC) inhibitor (IC50 = 7.5 to 16 nM). At low concentrations reduces release of pro-inflammatory cytokines, including TNF , INF , IL-1 and IL-1 , from LPS stimulated PBMCs in vitro . Exhibits anti-inflammatory effects in vivo . Improves functional recovery and attenuates tissue damage in a mouse model of traumatic brain injury.

top caption :

Histone deacetylase inhibitor

extended description :

Histone deacetylase inhibitor

chemical name text :

[6-[(Diethylamino)methyl]-2-naphthalenyl]methyl-N-[4-[(hydroxyamino)carbonyl]phenyl]carbamate hydrochloride

formula :

C24H27N3O4.HCl

formula text :

C24H27N3O4.HCl

cas num :

199657-29-9

USD :

124 USD

product details :

Histone deacetylase inhibitor

alt names :

ITF 2357

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage