6248/5 | Tocris Bioscience 6248/5 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

6248/5

catalog :

6248/5

quantity :

5 mg (also 25 mg)

price :

86 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Lim Y, Cho I, Rennke H, Cho G. β2-adrenergic receptor regulates ER-mitochondria contacts. Sci Rep. 2021;11:21477 pubmed publisher

image

image 1 :

Cat.No. 6248 - EHop 016 C25H30N6O CAS No. 1380432-32-5

product information

master code :

6248

SKU :

6248/5

product name :

EHop 016

unit size :

5 mg (also 25 mg)

description :

Rac inhibitor

target :

Rho GTPase Inhibitors

category :

Small Molecules

purity :

98%

observed molecular weight :

430.55

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

EHop 016 is a Rac inhibitor (IC50 = 1.1 M). Exhibits some selectivity for Rac1 and Rac3 over Cdc42. Blocks the interaction of Rac with guanine nucleotide exchange factor Vav2 in breast cancer cell lines expressing high levels of Rac activity and inhibits activity of Rac downstream effector PAK1. Also inhibits mammary tumor growth and metastasis in mice.

top caption :

Rac inhibitor

extended description :

Rac inhibitor

chemical name text :

N4-(9-Ethyl-9H-carbazol-3-yl)-N2-[3-(4-morpholinyl)propyl]-2,4-pyrimidinediamine

formula :

C25H30N6O

formula text :

C25H30N6O

cas num :

1380432-32-5

USD :

86 USD

product details :

Rac inhibitor

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage