6243/5 | Tocris Bioscience 6243/5 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

6243/5

catalog :

6243/5

quantity :

5 mg (also 25 mg)

price :

107 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Linke F, Johnson J, Kern S, Bennett C, Lourdusamy A, Lea D, et al. Identifying new biomarkers of aggressive Group 3 and SHH medulloblastoma using 3D hydrogel models, single cell RNA sequencing and 3D OrbiSIMS imaging. Acta Neuropathol Commun. 2023;11:6 pubmed publisher
Oh J, Nam T, Choi Y. Capsosiphon fulvescens Glycoproteins Enhance Probiotics-Induced Cognitive Improvement in Aged Rats. Nutrients. 2020;12: pubmed publisher

product information

master code :

6243

SKU :

6243/5

product name :

ML 385

unit size :

5 mg (also 25 mg)

description :

Nrf2 inhibitor; phenotypically lethal

target :

Nrf2 Inhibitors

category :

Small Molecules

purity :

98%

observed molecular weight :

511.59

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

ML 385 is an Nrf2 inhibitor. Blocks Nrf2 downstream target gene expression. Enhances cytotoxic effects of doxorubicin (Cat. No. 2252) or Taxol (Cat. No. 1097) in non-small cell lung cancer (NSCLC). Demonstrates selectivity for NSCLC cells with KEAP1 mutations.

top caption :

Nrf2 inhibitor; phenotypically lethal

extended description :

Nrf2 inhibitor; phenotypically lethal

chemical name text :

N-[4-[2,3-Dihydro-1-(2-methylbenzoyl)-1H-indol-5-yl]-5-methyl-2-thiazolyl]-1,3-benzodioxole-5-acetamide

formula :

C29H25N3O4S

formula text :

C29H25N3O4S

cas num :

846557-71-9

USD :

107 USD

product details :

Nrf2 inhibitor; phenotypically lethal

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage