6242/5 | Tocris Bioscience 6242/5 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

6242/5

catalog :

6242/5

quantity :

5 mg (also 25 mg)

price :

185 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Wang Eckhardt L, Becker I, Eckhardt M. The PGRMC1 Antagonist AG-205 Inhibits Synthesis of Galactosylceramide and Sulfatide. Cells. 2021;10: pubmed publisher
Chen Y, Knupp J, Arunagiri A, Haataja L, Arvan P, Tsai B. PGRMC1 acts as a size-selective cargo receptor to drive ER-phagic clearance of mutant prohormones. Nat Commun. 2021;12:5991 pubmed publisher

image

image 1 :

Cat.No. 6242 - AG 205 C22H23ClN6OS

product information

master code :

6242

SKU :

6242/5

product name :

AG 205

unit size :

5 mg (also 25 mg)

description :

Progesterone receptor membrane component 1 (Pgrmc1) ligand

target :

Additional Nuclear Receptor Compounds

category :

Small Molecules

purity :

97%

observed molecular weight :

454.98

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

AG 205 is a progesterone receptor membrane component 1 (Pgrmc1) ligand. Inhibits cell cycle progression and cell viability in cancer cell lines. Inhibits progesterone induced cytosolic Ca2+ increases in GnRH neurons in vitro .

top caption :

Progesterone receptor membrane component 1 (Pgrmc1) ligand

extended description :

Progesterone receptor membrane component 1 (Pgrmc1) ligand

chemical name text :

cis-2-[[1-(4-Chlorophenyl)-1H-tetrazol-5-yl]thio]-1-(1,2,3,4,4a,9b-hexahydro-2,8-dimethyl-5H-pyrido[4,3-b]indol-5-yl)-ethanone

formula :

C22H23ClN6OS

formula text :

C22H23ClN6OS

cas num :

442656-02-2

USD :

185 USD

product details :

Progesterone receptor membrane component 1 (Pgrmc1) ligand

storage :

Store at +4░C

more info or order :

Tocris Bioscience product webpage