6240/10 | Tocris Bioscience 6240/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

6240/10

catalog :

6240/10

quantity :

10 mg (also 50 mg)

price :

243 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Guillem Llobat P, Dovizio M, Bruno A, Ricciotti E, Cufino V, Sacco A, et al. Aspirin prevents colorectal cancer metastasis in mice by splitting the crosstalk between platelets and tumor cells. Oncotarget. 2016;7:32462-77 pubmed publisher

image

image 1 :

Cat.No. 6240 - DG 041 C23H15Cl4FN2O3S2 CAS No. 861238-35-9

product information

master code :

6240

SKU :

6240/10

product name :

DG 041

unit size :

10 mg (also 50 mg)

description :

Potent and selective EP3 antagonist; antiplatelet and antithrombotic

target :

Prostanoid Receptor Antagonists

category :

Small Molecules

purity :

98%

observed molecular weight :

592.32

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

DG 041 is a potent and selective EP3 antagonist (IC50 = 4.6 nM). Inhibits PGE2 facilitation of platelet aggregation in vitro and ex vivo . Displays good plasma and metabolic stability. Does not affect bleeding time in rats. Antiplatelet and antithrombotic.

top caption :

Potent and selective EP3 antagonist; antiplatelet and antithrombotic

extended description :

Potent and selective EP3 antagonist; antiplatelet and antithrombotic

chemical name text :

(2E)-3-[1-[(2,4-Dichlorophenyl)methyl]-5-fluoro-3-methyl-1H-indol-7-yl]-N-[(4,5-dichloro-2-thienyl)sulfonyl]-2-propenamide

formula :

C23H15Cl4FN2O3S2

formula text :

C23H15Cl4FN2O3S2

cas num :

861238-35-9

USD :

243 USD

product details :

Potent and selective EP3 antagonist; antiplatelet and antithrombotic

storage :

Store at +4░C

more info or order :

Tocris Bioscience product webpage