FPS ZM1 | Tocris Bioscience 6237 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

FPS ZM1

catalog :

6237

quantity :

10 mg (also 50 mg)

price :

70 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Uderhardt S, Martins A, Tsang J, Lämmermann T, Germain R. Resident Macrophages Cloak Tissue Microlesions to Prevent Neutrophil-Driven Inflammatory Damage. Cell. 2019;177:541-555.e17 pubmed publisher

product information

brand :

Tocris

master code :

6237

SKU :

6237/10

product name :

FPS ZM1

description :

High affinity antagonist of RAGE

target :

NFkB/IkB Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

99%

observed molecular weight :

327.85

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

High affinity antagonist of the receptor for advanced glycation end products (RAGE) (Ki = 25 nM). Blocks A binding to the V domain of RAGE and inhibits A 40- and A 42-induced cellular stress in RAGE-expressing cells in vitro and in the mouse brain in vivo . Blocks -secretase activity, A production, microglia activation and neuroinflammation in vivo . BBB permeable.

catalog number base :

6237

product keywords :

FPSZM1 Inhibitors Inhibits Antagonist RAGE Receptor for advanced glycation end products RAP RAGE antagonist peptide blood-brain barrier BBB permeable penetrant AB42 A A 42 Alzheimer's Disease NF-kB/IkB RAGE 6237,

extended description :

High affinity antagonist of RAGE

chemical name text :

4-Chloro-N-cyclohexyl-N-(phenylmethyl)benzamide

formula :

C 20 H 22 ClNO

formula text :

C20H22ClNO

cas num :

945714-67-0

2020 USD :

2021 USD :

70 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage