Bosentan | Tocris Bioscience 6232/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Bosentan

catalog :

6232/10

quantity :

10 mg (also 50 mg)

price :

97 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Reid J, Golubeva D, Boyd A, Hollands C, Henly C, Orlando L, et al. Human pluripotent stem cells identify molecular targets of trisomy 12 in chronic lymphocytic leukemia patients. Cell Rep. 2021;34:108845 pubmed publisher

image

image 1 :

Cat.No. 6232 - Bosentan C27H29N5O6S CAS No. 147536-97-8

product information

brand :

Tocris

master code :

6232

SKU :

6232/10

product name :

Bosentan

unit size :

10 mg (also 50 mg)

seo description :

High affinity dual ETA and ETB receptor antagonist;orally bioavailable

target :

Non-selective Endothelin Receptor Antagonists

category :

Small Molecules

purity :

98%

observed molecular weight :

551.61

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Bosentan is a high affinity dual ETA and ETB receptor antagonist (Ki values are 4.7 and 95 nM for ETA and ETB, respectively). Inhibits ET-1 induced contraction of isolated rat aorta and sarafotoxin S6C -induced contraction of rat trachea in vitro . Orally bioavailable.

top caption :

High affinity dual ETA and ETB receptor antagonist;orally bioavailable

extended description :

High affinity dual ETA and ETB receptor antagonist;orally bioavailable

chemical name text :

4-(1,1-Dimethylethyl)-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)[2,2 -bipyrimidin]-4-yl]benzenesulfonamide

formula :

C27H29N5O6S

formula text :

C27H29N5O6S

cas num :

147536-97-8

USD :

97 USD

product details :

High affinity dual ETA and ETB receptor antagonist;orally bioavailable

alt names :

Ro 47-0203

storage :

Store at +4░C

more info or order :

Tocris Bioscience product webpage