Dacomitinib | Tocris Bioscience 6231/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Dacomitinib

catalog :

6231/10

quantity :

10 mg (also 50 mg)

price :

312 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 6231 - Dacomitinib C24H25ClFN5O2 CAS No. 1110813-31-4

product information

brand :

Tocris

master code :

6231

SKU :

6231/10

product name :

Dacomitinib

unit size :

10 mg (also 50 mg)

seo description :

Potent irreversible pan ErbB inhibitor

target :

EGF Receptor Inhibitors

category :

Small Molecules

purity :

98%

observed molecular weight :

469.94

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Dacomitinib is a potent irreversible pan ErbB inhibitor (IC50 values are 6.0, 45.7 and 73.7 nM for EGFR, ERBB2 and ERBB4, respectively). Inhibits mutant and wild type forms of ErbB, including EGFR T780M, and shows activity in NSCLC cell lines sensitive and resistant to Iressa (Cat. No. 3000). Inhibits tumor growth. Orally bioavailable.

top caption :

Potent irreversible pan ErbB inhibitor

extended description :

Potent irreversible pan ErbB inhibitor

chemical name text :

(2E)-N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]-4-(1-piperidinyl)-2-butenamide

formula :

C24H25ClFN5O2

formula text :

C24H25ClFN5O2

cas num :

1110813-31-4

USD :

312 USD

product details :

Potent irreversible pan ErbB inhibitor

alt names :

PF00299804

storage :

Store at +4░C

more info or order :

Tocris Bioscience product webpage