H10 | Tocris Bioscience 6228 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

H10

catalog :

6228

quantity :

1 mg

price :

299 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

6228

SKU :

6228/1

product name :

H10

description :

PARP14 inhibitor; cell-permeable

target :

Poly(ADP-ribose) Polymerase Inhibitors

category :

Small Molecules

unit size :

1 mg

purity :

98%

observed molecular weight :

557.58

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

PARP14 inhibitor (IC50 = 490 nM). Exhibits 24- and 18-fold selectivity for PARP14 over PARP1 and TNKS1, respectively. Binds both the nicotinamide and adenine sites on PARP14. Inhibits PARP14 and induces apoptosis in HepG2 and RPMI-8226 in cancer cells in vitro .

catalog number base :

6228

product keywords :

PARP14 inhibitors inhibits apoptosis Poly(ADP-ribose) Polymerase Poly(ADP-ribose) Polymerase 6228,

extended description :

PARP14 inhibitor; cell-permeable

chemical name text :

3-(N-(2-(4-(2-(4-((3-Carbamoylphenyl)amino)-4-oxobutanamido)ethyl)-1H-1,2,3-triazol-1-yl)ethyl)sulfamoyl)benzoic acid

formula :

C 24 H 27 N 7 O 7 S

formula text :

C24H27N7O7S

cas num :

2084811-68-5

2020 USD :

299

2021 USD :

299 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage