product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
IC 87201
catalog :
6226
quantity :
10 mg (also 50 mg)
price :
133 USD
more info or order :
product information
brand :
Tocris
master code :
6226
SKU :
6226/10
product name :
IC 87201
description :
nNOS-PSD95 protein-protein interaction inhibitor; also antinociceptive and antidepressant
target :
Additional NMDA Receptor Compounds
category :
Small Molecules
unit size :
10 mg (also 50 mg)
purity :
99%
observed molecular weight :
309.15
url print :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Inhibits binding of the NMDA receptor postsynaptic density protein 95 kDa (PSD95) to nNOS (EC50 = 23.94 M), while not affecting the PSD95-ErbB4 interaction. Inhibits glutamate-induced cell death in cultured cortical neurons. Exhibits antinociceptive effects in inflammatory pain models in vivo . Also exhibits antidepressant-like activitiy in animal models.
catalog number base :
6226
product keywords :
IC87201 postsynaptic density protein 95 PSD95 nNOS NMDA protein-protein interactions inhibitors inhibits binding antinociceptive antidepressant NMDA Receptors nNOS 6226,
extended description :
nNOS-PSD95 protein-protein interaction inhibitor; also antinociceptive and antidepressant
chemical name text :
2-[(1H-Benzotriazol-6-ylamino)methyl]-4,6-dichlorophenol
formula :
C 13 H 10 Cl 2 N 4 O
formula text :
C13H10Cl2N4O
cas num :
866927-10-8
2020 USD :
133
2021 USD :
133 USD
storage :
Store at +4°C
more info or order :
company information

Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com800-343-7475
headquarters: UK
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