product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
Galiellalactone
catalog :
6218
quantity :
500 ug
price :
229 USD
more info or order :
Tocris Bioscience product webpage
product information
brand :
Tocris
master code :
6218
SKU :
6218/500U
product name :
Galiellalactone
description :
STAT3 inhibitor; active in vivo
target :
STAT Inhibitors
category :
Small Molecules
unit size :
500 ug
purity :
95%
observed molecular weight :
194.23
url print :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
STAT3 inhibitor. Irreversibly binds STAT3 and inhibits binding to DNA. Inhibits IL-6-dependent JAK/STAT signaling. Induces cell-cycle arrest in G2/M phase and apoptosis in androgen-insensitive prostate cancer cells via activation of ATM/ATR pathway. Also destabilizes microtubules and inhibits cell migration. Exhibits anticancer effects in a mouse tumor xenograft model.
catalog number base :
6218
product keywords :
STAT3 inhibitors inhibits IL-6 signaling anticancer in vivo active STAT 6218,
extended description :
STAT3 inhibitor; active in vivo
chemical name text :
(4S,5aR,7aR,7bS)-5,5a,6,7,7a,7b-Hexahydro-7b-hydroxy-4-methylindeno[1,7-bc]furan-2(4H)-one
formula :
C 11 H 14 O 3
formula text :
C11H14O3
cas num :
133613-71-5
2020 USD :
222
2021 USD :
229 USD
storage :
Store at -20°C
more info or order :
Tocris Bioscience product webpage
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK