ci-IP3/PM | Tocris Bioscience 6210/10U product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

ci-IP3/PM

catalog :

6210/10U

quantity :

10 ug

price :

295 USD

more info or order :

Tocris Bioscience product webpage

citations: 9

Reference
Genovese M, Guidone D, Buccirossi M, Borrelli A, Rodríguez Gimeno A, Bertozzi F, et al. Pharmacological potentiators of the calcium signaling cascade identified by high-throughput screening. PNAS Nexus. 2023;2:pgac288 pubmed publisher
Arjona S, Allen C, Santerre M, Gross S, Soboloff J, Booze R, et al. Disruption of Mitochondrial-associated ER membranes by HIV-1 tat protein contributes to premature brain aging. CNS Neurosci Ther. 2023;29:365-377 pubmed publisher
Arige V, Terry L, Wagner L, Malik S, Baker M, Fan G, et al. Functional determination of calcium-binding sites required for the activation of inositol 1,4,5-trisphosphate receptors. Proc Natl Acad Sci U S A. 2022;119:e2209267119 pubmed publisher
Yuan Y, Ja x15b lan D, Rahman T, Bolsover S, Arige V, Wagner L, et al. Segregated cation flux by TPC2 biases Ca2+ signaling through lysosomes. Nat Commun. 2022;13:4481 pubmed publisher
Arige V, Terry L, Malik S, Knebel T, Wagner Ii L, Yule D. CREB regulates the expression of type 1 inositol 1,4,5-trisphosphate receptors. J Cell Sci. 2021;134: pubmed publisher
Yoast R, Emrich S, Zhang X, Xin P, Arige V, Pathak T, et al. The Mitochondrial Ca2+ uniporter is a central regulator of interorganellar Ca2+ transfer and NFAT activation. J Biol Chem. 2021;297:101174 pubmed publisher
Arige V, Emrich S, Yoast R, Trebak M, Yule D. A protocol for detecting elemental calcium signals (Ca2+ puffs) in mammalian cells using total internal reflection fluorescence microscopy. STAR Protoc. 2021;2:100618 pubmed publisher
Emrich S, Yoast R, Xin P, Arige V, Wagner L, Hempel N, et al. Omnitemporal choreographies of all five STIM/Orai and IP3Rs underlie the complexity of mammalian Ca2+ signaling. Cell Rep. 2021;34:108760 pubmed publisher
Aulestia F, Groeling J, Bomfim G, Costiniti V, Manikandan V, Chaloemtoem A, et al. Fluoride exposure alters Ca2+ signaling and mitochondrial function in enamel cells. Sci Signal. 2020;13: pubmed publisher

product information

brand :

Tocris

master code :

6210

SKU :

6210/10U

product name :

ci-IP3/PM

unit size :

10 ug

seo description :

Caged inositol triphosphate

target :

Caged Compounds

category :

Small Molecules

purity :

98%

observed molecular weight :

1171.87

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

ci-IP3/PM is a caged inositol triphosphate. Cell permeable. UV photolysis ( = 330 nm) in HeLa cells releases i-IP3, promoting Ca2+-release from internal stores. . F 127 (Cat. No. 6253) for the solubilization of ci-IP3/PM is also available.

top caption :

Caged inositol triphosphate

extended description :

Caged inositol triphosphate

chemical name text :

6-O-[(4,5-Dimethoxy-2-nitrophenyl)methyl]-2,3-O-(1-methylethylidene)-D-myo-Inositol 1,4,5-tris[bis[(1-oxopropoxy)methyl]phosphate]

formula :

C42H64NO31P3

formula text :

C42H64NO31P3

cas num :

1009832-82-9

USD :

295 USD

product details :

Caged inositol triphosphate

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage