chemical

J 2156

6201

10 mg (also 50 mg)

275 USD

6201

6201/10

J 2156

Selective high affinity human sst4 agonist

Somatostatin Receptor Agonists

Small Molecules

10 mg (also 50 mg)

98%

582.6

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High affinity human somatostatin receptor 4 (sst4) agonist (Ki = 1.2 nM). Displays 400-fold selectivity for human sst4 over other human sst receptor subtypes. Exhibits 2 to 3-fold more potent agonism in vitro than endogenous ligands somatostatin-14 (Cat. No. 1157) and somatostatin-28 (Cat. No. 1165). Reduces inflammatory airway hyperresponsiveness in acute and chronic airway inflammation models in mice. Exhibits anxiolytic effects in elevated plus maze test in mice.

6201

J2156 human somatostatin receptor 4 sst4 superagonist agonists agonism 848647-56-3 anti-inflammatory 848647-56-3 Somatostatin Receptors 6201,

Selective high affinity human sst4 agonist

(1 S,2S)-4-Amino-N-(1 -carbamoyl-2 -phenylethyl)-2-(4 -methyl-1 -naphthalenesulfonylamino)butanamide trifluoroacetate

C 24 H 28 N 4 O 4 S.C 2 HF 3 O 2

C24H28N4O4S.C2HF3O2

269

275 USD

Store at -20°C