SSR 149415 | Tocris Bioscience 6195 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

SSR 149415

catalog :

6195

quantity :

10 mg (also 50 mg)

price :

218 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

6195

SKU :

6195/10

product name :

SSR 149415

description :

Potent and selective vasopressin V1B antagonist

target :

Vasopressin Receptor Antagonists

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

630.11

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent and selective vasopressin V1B antagonist (Ki values are 3.7 and 1.3 nM for native and recombinant rat V1b receptors, respectively). Displays 70-fold selectively for rat V1B over V1A, V2 oxytoxin and a range of other receptors and ion channels. Inhibits AVP-induced glucagon release in In-R1-G9 -pancreatic cells in vitro . Inhibits stress-induced ACTH release and exhibits anxiolytic-like effects in anxiety models. Orally bioavailable.

catalog number base :

6195

product keywords :

SSR149415 vasopressin receptor V1b potent selective antagonists antagonism orally bioavailable Nelivaptan Vasopressin Receptors 6195,

extended description :

Potent and selective vasopressin V1B antagonist

chemical name text :

(2S,4R)-1-[(3R)-5-Chloro-1-[(2,4-dimethoxyphenyl)sulfonyl]-2,3-dihydro-3-(2-methoxyphenyl)-2-oxo-1H-indol-3-yl]-4-hydroxy-N,N-dimethyl-2-pyrrolidinecarboxamide

formula :

C 30 H 32 ClN 3 O 8 S

formula text :

C30H32ClN3O8S

cas num :

439687-69-1

2020 USD :

209

2021 USD :

218 USD

alt names :

Nelivaptan

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage