SK 216 | Tocris Bioscience 6187 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

SK 216

catalog :

6187

quantity :

10 mg (also 50 mg)

price :

187 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

6187

SKU :

6187/10

product name :

SK 216

description :

Plasminogen activator inhibitor-1 (PAI-1) inhibitor

target :

PAI-1 Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

533.52

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Plasminogen activator inhibitor-1 (PAI-1) inhibitor. Inhibits VEGF-induced migration and tube formation in HUVECs. Also attenuates TGF- dependent epithelial-mesenchymal transition and fibroblast to myofibroblast differentiation in vitro . Reduces size and weight of subcutaneous tumors, and inhibits metastasis and angiogenesis in vivo . Reduces bleomycin-induced pulmonary fibrosis in vivo . Orally bioavailable.

catalog number base :

6187

product keywords :

SK216 plasminogen activator inhibitor-1 inhibitors inhibits PAI-1 angiogenesis antiangiogenesis Mesenchymal Stem Cells Antiangiogenics Plasminogen Activator Inhibitor 1 6187, p21-Activated Kinases, p21-Activated Kinase, PAKs

extended description :

Plasminogen activator inhibitor-1 (PAI-1) inhibitor

chemical name text :

2-[5-[[6-[5-(1,1-Dimethylethyl)-2-benzoxazolyl]-2-naphthalenyl]oxy]pentyl]propanedioic acid disodium salt

formula :

C 29 H 29 NO 6 Na 2

formula text :

C29H29NO6Na2

cas num :

654080-03-2

2020 USD :

181

2021 USD :

187 USD

storage :

Desiccate at RT

more info or order :

Tocris Bioscience product webpage