product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
SK 216
catalog :
6187/10
quantity :
10 mg (also 50 mg)
price :
243 USD
more info or order :
image
image 1 :
Tocris Bioscience 6187/10 image 1
Cat.No. 6187 - SK 216 C29H29NO6Na2 CAS No. 654080-03-2
product information
brand :
Tocris
master code :
6187
SKU :
6187/10
product name :
SK 216
unit size :
10 mg (also 50 mg)
seo description :
Plasminogen activator inhibitor-1 (PAI-1) inhibitor
target :
PAI-1 Inhibitors
category :
Small Molecules
purity :
98%
observed molecular weight :
533.52
url print :
?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
SK 216 is a plasminogen activator inhibitor-1 (PAI-1) inhibitor. Inhibits VEGF-induced migration and tube formation in HUVECs. Also attenuates TGF- dependent epithelial-mesenchymal transition and fibroblast to myofibroblast differentiation in vitro . Reduces size and weight of subcutaneous tumors, and inhibits metastasis and angiogenesis in vivo . Reduces bleomycin-induced pulmonary fibrosis in vivo . Orally bioavailable.
top caption :
Plasminogen activator inhibitor-1 (PAI-1) inhibitor
extended description :
Plasminogen activator inhibitor-1 (PAI-1) inhibitor
chemical name text :
2-[5-[[6-[5-(1,1-Dimethylethyl)-2-benzoxazolyl]-2-naphthalenyl]oxy]pentyl]propanedioic acid disodium salt
formula :
C29H29NO6Na2
formula text :
C29H29NO6Na2
cas num :
654080-03-2
USD :
243 USD
product details :
Plasminogen activator inhibitor-1 (PAI-1) inhibitor
storage :
Desiccate at RT
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK