product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
Pemetrexed
catalog :
6185
quantity :
50 mg
price :
63 USD
more info or order :
Tocris Bioscience product webpage
product information
brand :
Tocris
master code :
6185
SKU :
6185/50
product name :
Pemetrexed
description :
Thymidylate synthetase inhibitor, also inhibits dihydrofolate reductase, GARFT and AICART
target :
Dihydrofolate Reductase Inhibitors
category :
Small Molecules
unit size :
50 mg
purity :
98%
observed molecular weight :
427.41
url print :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
High affinity dihydrofolate reductase inhibitor (Ki = 7 nM). Also inhibits thymidylate synthase, AICART and glycinamide ribonucleotide formyltransferase (Ki values are 109 nM, and 3.5 M and 9.3 M, respectively). Indirectly activates AMPK. Inhibits proliferation of cancer cell lines in vitro .
catalog number base :
6185
product keywords :
high affinity dihydrofolate reductase inhibitor inhibitors DHFR thymidylate synthase TS AICART AICARFT aminoimidazolecarboxamide ribonucleotide formyltransferase glycinamide GARFT chemotherapeutic antifolate antimetabolite AICARFT Dihydrofolate Reductase Other Transferases Thymidylate Synthetase 6185,
extended description :
Thymidylate synthetase inhibitor, also inhibits dihydrofolate reductase, GARFT and AICART
chemical name text :
N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid
formula :
C 20 H 21 N 5 O 6
formula text :
C20H21N5O6
cas num :
137281-23-3
2020 USD :
61
2021 USD :
63 USD
storage :
Store at +4°C
more info or order :
Tocris Bioscience product webpage
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK