CVT 313 | Tocris Bioscience 6174/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

CVT 313

catalog :

6174/10

quantity :

10 mg (also 50 mg)

price :

223 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Musa J, Cidre Aranaz F, Aynaud M, Orth M, Knott M, Mirabeau O, et al. Cooperation of cancer drivers with regulatory germline variants shapes clinical outcomes. Nat Commun. 2019;10:4128 pubmed publisher

image

image 1 :

Cat.No. 6174 - CVT 313 C20H28N6O3 CAS No. 199986-75-9

product information

brand :

Tocris

master code :

6174

SKU :

6174/10

product name :

CVT 313

unit size :

10 mg (also 50 mg)

seo description :

Cdk2 and cdk5 inhibitor

target :

Cyclin-dependent Kinase Inhibitors

category :

Small Molecules

purity :

98%

observed molecular weight :

400.47

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

CVT 313 is a cyclin-dependent kinase 2 (cdk2) inhibitor (reported IC50 values are 0.18 to 0.5 M). Also inhibits cdk5 in sub-micromolar range (IC50 = 0.42 M). Displays >7-fold selectivity for cdk2 and cdk5 over other cdks. Inhibits proliferation rat neonatal aortic smooth muscle cells and a range of tumor cells lines in vitro . Inhibits restenosis in a rat carotid artery injury model.

top caption :

Cdk2 and cdk5 inhibitor

extended description :

Cdk2 and cdk5 inhibitor

chemical name text :

2,2 -[[6-[[(4-Methoxyphenyl)methyl]amino]-9-(1-methylethyl)-9H-purin-2-yl]imino]bis[ethanol]

formula :

C20H28N6O3

formula text :

C20H28N6O3

cas num :

199986-75-9

USD :

223 USD

product details :

Cdk2 and cdk5 inhibitor

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage