MLS 1547 | Tocris Bioscience 6171/5 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

MLS 1547

catalog :

6171/5

quantity :

5 mg (also 25 mg)

price :

101 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Tan Z, Lei Z, Yan Z, Ji X, Chang X, Cai Z, et al. Exploiting D2 receptor β-arrestin2-biased signalling to suppress tumour growth of pituitary adenomas. Br J Pharmacol. 2021;178:3570-3586 pubmed publisher
Mann A, Keen A, Mark H, Dasgupta P, Javitch J, Canals M, et al. New phosphosite-specific antibodies to unravel the role of GRK phosphorylation in dopamine D2 receptor regulation and signaling. Sci Rep. 2021;11:8288 pubmed publisher

image

image 1 :

Cat.No. 6171 - MLS 1547 C19H19ClN4O CAS No. 315698-36-3

product information

brand :

Tocris

master code :

6171

SKU :

6171/5

product name :

MLS 1547

unit size :

5 mg (also 25 mg)

seo description :

G protein-biased D2 partial agonist

target :

Dopamine D2 Receptor Agonists

category :

Small Molecules

purity :

98%

observed molecular weight :

354.83

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

MLS 1547 is a G protein-biased D2 receptor partial agonist (Ki = 1.2 M). Stimulates D2 receptor G protein-mediated signaling and acts as an antagonist of dopamine-mediated -arrestin recruitment at D2 receptors.

top caption :

G protein-biased D2 partial agonist

extended description :

G protein-biased D2 partial agonist

chemical name text :

5-Chloro-7-[[4-(2-pyridinyl)-1-piperazinyl]methyl]-8-quinolinol

formula :

C19H19ClN4O

formula text :

C19H19ClN4O

cas num :

315698-36-3

USD :

101 USD

product details :

G protein-biased D2 partial agonist

storage :

Store at +4░C

more info or order :

Tocris Bioscience product webpage