Cinacalcet hydrochloride | Tocris Bioscience 6170 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Cinacalcet hydrochloride

catalog :

6170

quantity :

10 mg (also 50 mg)

price :

96 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

6170

SKU :

6170/10

product name :

Cinacalcet hydrochloride

description :

Allosteric Calcium-sensing receptor (CaSR) agonist; also CYP2D2 inhibitor and Ca2+ channel blocker; orally bioavailable

target :

Calcium-Sensing Receptor Agonists

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

393.87

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Calcium-sensing receptor (CaSR) allosteric agonist. Activates CaSR signaling in cellular proliferation and phosphatidylinositol (PI) hydrolysis assays. Reduces serum parathyroid hormone levels in rats. Also potent CYP2D2 inhibitor (IC50 = 87 nM) and L-type calcium channel blocker. Orally bioavailable.

catalog number base :

6170

product keywords :

AMG073 calcium-sensing receptor CaSR allosteric agonists agonism calcimimetic CYP2D2 inhibitors inhibits L-type calcium channel blockers Sensipar AMG 073 Calcium-Sensing Receptor Cytochrome P450 Cav1.x Channels 6170,

extended description :

Allosteric Calcium-sensing receptor (CaSR) agonist; also CYP2D2 inhibitor and Ca2+ channel blocker; orally bioavailable

chemical name text :

N-[(1R)-1-(1-Naphthyl)ethyl]-3-[3-(trifluoromethyl)phenyl]propan-1-amine hydrochloride

formula :

C 22 H 22 F 3 N.HCl

formula text :

C22H22F3N.HCl

cas num :

364782-34-3

2020 USD :

2021 USD :

96 USD

alt names :

AMG 073

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage