chemical

A 196

6167/10

10 mg (also 50 mg)

152 USD

6167

6167/10

A 196

Potent and selective SUV420H1/H2 inhibitor

Lysine Methyltransferase Inhibitors

10 mg (also 50 mg)

Small Molecules

98%

Store at +4°C

359.25

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A 196 is a potent and selective SUV420H1/H2 inhibitor (IC50 values are 25 and 144 nM respectively) that exhibits 100-fold selectivity over other histone methyltransferases and non-epigenetic targets. A 196 inhibits the di- and tri-methylation of H4K20me in multiple cell lines (IC50 1 M). . To request the negative control for A 196, please fill out the SGC 2043 request form on the SGC website.

A196 methyltransferases histones inhibitors inhibits HMTs MLL leukemia mll-rearranged H4K20me potent selective Other Lysine Methyltransferases Lysine Methyltransferases 6167,

Potent and selective SUV420H1/H2 inhibitor

6,7-Dichloro-N-cyclopentyl-4-(4-pyridinyl)-1-phthalazinamine

C18H16Cl2N4

C18H16Cl2N4

1982372-88-2

147

152 USD

Potent and selective SUV420H1/H2 inhibitor