product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
AC 265347
catalog :
6165
quantity :
10 mg (also 50 mg)
price :
123 USD
more info or order :
Tocris Bioscience product webpage
product information
brand :
Tocris
master code :
6165
SKU :
6165/10
product name :
AC 265347
description :
Biased allosteric modulator of calcium-sensing receptor (CaSR)
target :
Calcium-Sensing Receptor Modulators
category :
Small Molecules
unit size :
10 mg (also 50 mg)
purity :
99%
observed molecular weight :
283.39
url print :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
CaSR biased allosteric modulator (pEC50 = 7.8-8.1). Calcimimetic. Displays ability to bias signalling towards the accumulation of pERK1/2 and IP1. Reduces parathyroid hormone (PTH) levels in rat serum without inducing the release of calcitonin. Exhibits no significant activation of human GABAB or type I PTH receptors. Orally active.
catalog number base :
6165
product keywords :
AC265347 CaSR biased allosteric modulator calcimimetic parathyroid homrone PTH calcitonin PERK1/2 IP1 accumulation orally active Calcium-Sensing Receptor 6165,
extended description :
Biased allosteric modulator of calcium-sensing receptor (CaSR)
chemical name text :
-(2,4-Dimethylphenyl)- -methyl-2-benzothiazolemethanol
formula :
C 17 H 17 NOS
formula text :
C17H17NOS
cas num :
1253901-26-6
2020 USD :
120
2021 USD :
123 USD
storage :
Store at +4°C
more info or order :
Tocris Bioscience product webpage
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK