VE 821 | Tocris Bioscience 6160 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

VE 821

catalog :

6160

quantity :

25 mg

price :

304 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

6160

SKU :

6160/25

product name :

VE 821

description :

High affinity and selective ATP-competitive ATR inhibitor

target :

ATM and ATR Kinase Inhibitors

category :

Small Molecules

unit size :

25 mg

purity :

98%

observed molecular weight :

368.41

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

High affinity and selective ATP-competitive ATR inhibitor (Ki = 13 nM). Exhibits 75-fold selectivity for ATR over related kinases mTOR, DNA-PK, PI 3-K and PIKKs (Ki values are 1, 2.2, 3.9 and 16 M, respectively) and a panel of other kinases. Induces cell death in colon cancer cell lines in vitro and sensitizes tumor cells to treatment with DNA damaging anticancer agents.

catalog number base :

6160

product keywords :

VE821 ATR Ataxia telangiectasia and Rad3 related kinases inhibitors inhibits high affinity selective sensitizes sensitizing DNA damage damaging ATM & ATR Kinase 6160,

extended description :

High affinity and selective ATP-competitive ATR inhibitor

chemical name text :

3-Amino-6-[4-(methlsulfonyl)phenyl)-N-phenyl-2-pyrazinecarboxamide

formula :

C 18 H 16 N 4 O 3 S

formula text :

C18H16N4O3S

cas num :

1232410-49-9

2020 USD :

295

2021 USD :

304 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage