4,9-Anhydrotetrodotoxin | Tocris Bioscience 6159 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

4,9-Anhydrotetrodotoxin

catalog :

6159

quantity :

100 ug

price :

227 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Vysokov N, McMahon S, Raouf R. The role of NaV channels in synaptic transmission after axotomy in a microfluidic culture platform. Sci Rep. 2019;9:12915 pubmed publisher

product information

brand :

Tocris

master code :

6159

SKU :

6159/100U

product name :

4,9-Anhydrotetrodotoxin

description :

Potent and selective Nav1.6 channel blocker

target :

Voltage-gated Sodium Channel Blockers

category :

Small Molecules

unit size :

100 ug

purity :

98%

observed molecular weight :

301.25

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent and selective Nav1.6 channel blocker (IC50 values are 7.8, 341, 988, 1260, 1270, 78500 and 30000 nM for Nav1.6, Nav1.3, Nav1.4, Nav1.2, Nav1.7, Nav1.5 and Nav1.8). Derivative of tetrodotoxin (Cat. No. 1078).

catalog number base :

6159

product keywords :

Na+ channel blockers sodium Nav 1.6 channels voltage-gated voltage-dependent potent selective ttx 4,9-anhydro-TTX Voltage-gated Sodium Channels 6159,

extended description :

Potent and selective Nav1.6 channel blocker

chemical name text :

(4S,5aS,6S,8R,9S,10S,11S,11aR,12R)-2-Amino-1,4,5a,6,8,9,10,11-octahydro-9-(hydroxymethyl)-6,10-epoxy-4,8,11a-metheno-11aH-oxocino[4,3-f][1,3,5]oxadiazepine-6,9,11-triol

formula :

C 11 H 15 N 3 O 7

formula text :

C11H15N3O7

cas num :

13072-89-4

2020 USD :

218

2021 USD :

227 USD

alt names :

4,9-anhydro-TTX

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage