product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
(S)-Equol
catalog :
6158
quantity :
10 mg (also 50 mg)
price :
122 USD
more info or order :
citations: 1
Reference
Zhang T, Hu Q, Shi L, Qin L, Zhang Q, Mi M. Equol Attenuates Atherosclerosis in Apolipoprotein E-Deficient Mice by Inhibiting Endoplasmic Reticulum Stress via Activation of Nrf2 in Endothelial Cells. PLoS ONE. 2016;11:e0167020 pubmed publisher
product information
brand :
Tocris
master code :
6158
SKU :
6158/10
product name :
(S)-Equol
description :
Potent estrogen receptor (ER ) agonist; dihydrotestosterone antagonist
target :
Estrogen and Related Receptor Agonists
category :
Small Molecules
unit size :
10 mg (also 50 mg)
purity :
98%
observed molecular weight :
242.27
url print :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Potent estrogen receptor (ER ) agonist (EC50 = 65 nM). Exhibits 13-fold selectivity for ER over ER . Atheroprotective. Protects against t-BHP induced apoptosis and attenuates ER stress in HUVECs. Activates Nrf2 signaling in vitro and in vivo . Inhibits tumor growth. Also dihydrotestosterone antagonist in vivo .
catalog number base :
6158
product keywords :
agonist estrogen receptor beta agonist ERb ERbeta ER Nrf2 Estrogen and Related Receptors Androgen Receptor 6158,
extended description :
Potent estrogen receptor (ER ) agonist; dihydrotestosterone antagonist
chemical name text :
(3S)-3,4-Dihydro-3-(4-hydroxyphenyl)-2H-1-benzopyran-7-ol
formula :
C 15 H 14 O 3
formula text :
C15H14O3
cas num :
531-95-3
2020 USD :
122
2021 USD :
122 USD
storage :
Store at -20°C
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK