LDN 214117 | Tocris Bioscience 6152 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

LDN 214117

catalog :

6152

quantity :

10 mg (also 50 mg)

price :

208 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

6152

SKU :

6152/10

product name :

LDN 214117

description :

Potent and selective ALK2 inhibitor

target :

BMP and Other Activin Receptor Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

419.52

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent and selective inhibitor of type I bone morphogenic protein (BMP) receptor ALK2 (IC50 = 24 nM). Shows preference for ALK1 and ALK2 over ALK3 and 164-fold selectivity for BMP6 inhibition (IC50 = 100 nM) over TGF- 1. Exhibits improved kinome selectivity over K 02288 (Cat.No. 4986) and low cytotoxicity.

catalog number base :

6152

product keywords :

LDN214117 Inhibitors Inhibits ALK1 ALK2 BMP Bone morphogenic protein BMP6 TGF- 1 TGF-b1 TGF-beta1 kinase activin receptor-like kinases BMP and Other Activin Receptors 6152,

extended description :

Potent and selective ALK2 inhibitor

chemical name text :

1-[4-[6-Methyl-5-(3,4,5-trimethoxyphenyl)-3-pyridinyl]phenyl]piperazine

formula :

C 25 H 29 N 3 O 3

formula text :

C25H29N3O3

cas num :

1627503-67-6

2020 USD :

203

2021 USD :

208 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage