LDN 212854 | Tocris Bioscience 6151 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

LDN 212854

catalog :

6151

quantity :

50 mg

price :

861 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

6151

SKU :

6151/50

product name :

LDN 212854

description :

Potent bone morphogenetic protein type I (ALK) inhibitor

target :

ALK Inhibitors

category :

Small Molecules

unit size :

50 mg

purity :

98%

observed molecular weight :

406.48

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent ALK inhibitor (IC50 values are 1.3, 2.4, 85.8, 2,133 and 9,276 nM for ALK2, ALK1, ALK3, ALK4 and ALK5, respectively). Exhibits selectivity for ALK2 over ALK4 and ALK5 in cellular assays. Inhibits heterotopic ossification in a mutant ALK2 mouse model of fibrodysplasia ossificans progressiva. Also exhibits activity against RIPK2, ABL1 and PDGFR- (IC50 values 100 nM).

catalog number base :

6151

product keywords :

LDN212854 ALK inhibitors inhibits potent in vivo active BMP1 ALK2 bone morphogenetic protein type I BMP and Other Activin Receptors 6151,

extended description :

Potent bone morphogenetic protein type I (ALK) inhibitor

chemical name text :

5-(6-(4-(1-Piperazinyl)phenyl)pyrazolo[1,5-a]pyrimidin-3-yl)quinoline

formula :

C 25 H 22 N 6

formula text :

C25H22N6

cas num :

1432597-26-6

2020 USD :

861

2021 USD :

861 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage