PA Janelia Fluor 646, SE | Tocris Bioscience 6150/300U product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

PA Janelia Fluor 646, SE

catalog :

6150/300U

quantity :

300 ug

price :

176 USD

more info or order :

Tocris Bioscience product webpage

citations: 3

Reference
Su P, You L, Beerens C, Bezstarosti K, Demmers J, Pabst M, et al. Microscopy-based single-cell proteomic profiling reveals heterogeneity in DNA damage response dynamics. Cell Rep Methods. 2022;2:100237 pubmed publisher
Genshaft A, Ziegler C, Tzouanas C, Mead B, Jaeger A, Navia A, et al. Live cell tagging tracking and isolation for spatial transcriptomics using photoactivatable cell dyes. Nat Commun. 2021;12:4995 pubmed publisher
Kwan J, Nguyen T, Teves S. Visualizing Transcription Factor Binding on Mitotic Chromosomes Using Single-Molecule Live-Cell Imaging. Methods Mol Biol. 2019;2038:239-250 pubmed publisher

product information

brand :

Tocris

MasterCode :

6150

SKU :

6150/300U

product name :

PA Janelia Fluor 646, SE

target :

Photoactivatable Dyes

category :

Small Molecules

unit size :

300 ug

purity :

90%

observed molecular weight :

617.74

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

PA Janelia Fluor 646, SE is a photoactivatable fluorescent dye; supplied as an NHS ester for coupling to primary amine groups. Non-fluorescent until activated at 365 nm. NHS ester can be converted to relevant substrate for use in self-labeling tag systems, e.g. HaloTag and SNAP-tag . Suitable for single molecule tracking and super resolution microscopy in live cells, specifically live cell sptPALM and fixed cell PALM. Can be multiplexed with PA Janelia Fluor 549, SE (Cat. No. 6149) to perform two-colour sptPALM in live cells with activation at 405nm. Cell permeable. Excitation maximum = 649 - 651 nm; emission maximum = 663 - 665 nm. Upon protein conjugation the efficiencies of photoconversion improve substantially. Low background staining. . Please see the protocol for further information on protein/antibody labeling and conjugation. . HaloTag is a trademark of Promega Corporation, and SNAP-tag is a trademark of New England BioLabs, Inc.

extended description :

Red photoactivatable dye (Reactive group: NHS ester). Applications: super resolution microscopy (PALM), single molecule tracking and live cell imaging

chemical name text :

2,5-Dioxo-1-pyrrolidinyl 3,7-di-1-azetidinyl-2 -diazo-5,5-dimethyl-2 ,3 -dihydro-5H-3 -oxospiro[dibenzo[b,e]siline-10,1 -indene]-6 -carboxylate

formula :

C 34 H 31 N 5 O 5 Si

formula text :

C34H31N5O5Si

cas num :

2093120-32-0

USD :

176 USD

product details :

Red photoactivatable dye (Reactive group: NHS ester). Applications: super resolution microscopy (PALM), single molecule tracking and live cell imaging

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage