NVS PAK1 1 | Tocris Bioscience 6132/5 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

NVS PAK1 1

catalog :

6132/5

quantity :

5 mg (also 25 mg)

price :

139 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Brown T, Hashimoto H, Finseth L, Wood T, Macklin W. PAK1 positively regulates oligodendrocyte morphology and myelination. J Neurosci. 2021;: pubmed publisher

product information

brand :

Tocris

catalog number base :

6132

SKU :

6132/5

product name :

NVS PAK1 1

units size :

5 mg (also 25 mg)

description :

Potent and selective PAK1 inhibitor

target :

PAK Inhibitors

category :

Small Molecules

purity :

98%

observed molecular weight :

479.93

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

NVS PAK1 1 is a potent and selective PAK1 inhibitor (IC50 = 5 nM) that displays selective for PAK1 over PAK2 and a panel of 442 kinases. NVS PAK1 1 inhibits autophosphorylation of PAK1 in KRAS-mutated pancreatic cancer cell lines. . A negative control for NVS PAK1 1 is also available; NVS PAK1 C .

top caption :

Potent and selective PAK1 inhibitor

extended description :

Potent and selective PAK1 inhibitor

chemical name text :

(3S)-3-(2-Chloro-5-(2,2-difluoroethyl)-8-fluoro-5H-dibenzo[b,e][1,4]diazepin-11-ylamino)-N-isopropylpyrrolidine-1-carboxamide

formula :

C23H25ClF3N5O

formula text :

C23H25ClF3N5O

cas num :

1783816-74-9

USD :

139 USD

product details :

Potent and selective PAK1 inhibitor

storage :

Store at -20Â°C

more info or order :

Tocris Bioscience product webpage