GSK 343 | Tocris Bioscience 6128 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

GSK 343

catalog :

6128

quantity :

10 mg (also 50 mg)

price :

181 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

6128

SKU :

6128/10

product name :

GSK 343

description :

Potent and selective SAM-competitive EZH2 inhibitor

target :

EZH2 Inhibitor

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

541.69

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent and selective SAM-competitive EZH2 inhibitor (IC50 = 4 nM). Exhibits 60 fold selectivity for EZH2 over EZH1 and a range of other methyltransferases. Decreases H3K27me3 levels in breast cancer cells in vitro . Inhibits proliferation of prostate cancer cell lines in vitro .

catalog number base :

6128

product keywords :

GSK343 potent and selective EZH2 inhibitors inhibits lysine methyltransferase PRC2 polycomb repressive complex 2 Lysine Methyltransferases EZH2 6128, EZH 2, ENX 1, ENX1, KMT6, KMT 6

extended description :

Potent and selective SAM-competitive EZH2 inhibitor

chemical name text :

N-[(1,2-Dihydro-6-methyl-2-oxo-4-propyl-3-pyridinyl)methyl]-1-(1-methylethyl)-6-[2-(4-methyl-1-piperazinyl)-4-pyridinyl]-1H-indazole-4-carboxamide

formula :

C 31 H 39 N 7 O 2

formula text :

C31H39N7O2

cas num :

1346704-33-3

2020 USD :

175

2021 USD :

181 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage