OB 24 hydrochloride | Tocris Bioscience 6119/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

OB 24 hydrochloride

catalog :

6119/10

quantity :

10 mg (also 50 mg)

price :

207 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Khojandi N, Kuehm L, Piening A, Donlin M, Hsueh E, Schwartz T, et al. Oxidized Lipoproteins Promote Resistance to Cancer Immunotherapy Independent of Patient Obesity. Cancer Immunol Res. 2021;9:214-226 pubmed publisher
Kuehm L, Khojandi N, Piening A, Klevorn L, Geraud S, McLaughlin N, et al. Fructose Promotes Cytoprotection in Melanoma Tumors and Resistance to Immunotherapy. Cancer Immunol Res. 2021;9:227-238 pubmed publisher

product information

brand :

Tocris

catalog number base :

6119

SKU :

6119/10

product name :

OB 24 hydrochloride

units size :

10 mg (also 50 mg)

description :

Potent and selective heme oxygenase 1 (HO-1) inhibitor

target :

Heme Oxygenase Inhibitors

category :

Small Molecules

purity :

98%

observed molecular weight :

373.67

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

OB 24 hydrochloride is a potent and selective heme oxygenase 1 (HO-1) inhibitor (IC50 values are 1.9 and >100 M for HO-1 and HO-2 respectively), reduces protein carbonylation and reactive oxygen species formation in advanced prostate cancer cells (PCA). Inhibits cell proliferation in vitro and PCA tumor growth and lymph node/lung metastases in vivo . Synergizes with Taxol (Cat. No. 1097).

top caption :

Potent and selective heme oxygenase 1 (HO-1) inhibitor

extended description :

Potent and selective heme oxygenase 1 (HO-1) inhibitor

chemical name text :

1-[[2-[2-(4-Bromophenyl)ethyl]-1,3-dioxolan-2-yl]methyl]-1H-imidazole hydrochloride

formula :

C15H17BrN2O2.HCl

formula text :

C15H17BrN2O2.HCl

cas num :

939825-12-4

USD :

207 USD

product details :

Potent and selective heme oxygenase 1 (HO-1) inhibitor

storage :

Desiccate at RT

more info or order :

Tocris Bioscience product webpage