1S,3R-RSL3 | Tocris Bioscience 6118/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

1S,3R-RSL3

catalog :

6118/10

quantity :

10 mg (also 50 mg)

price :

282 USD

more info or order :

Tocris Bioscience product webpage

citations: 4

Reference
Puylaert P, Roth L, Van Praet M, Pintelon I, Dumitrascu C, van Nuijs A, et al. Effect of erythrophagocytosis-induced ferroptosis during angiogenesis in atherosclerotic plaques. Angiogenesis. 2023;26:505-522 pubmed publisher
Hanniford D, Ulloa Morales A, Karz A, Berzoti Coelho M, Moubarak R, Sánchez Sendra B, et al. Epigenetic Silencing of CDR1as Drives IGF2BP3-Mediated Melanoma Invasion and Metastasis. Cancer Cell. 2020;37:55-70.e15 pubmed publisher
Bi J, Yang S, Li L, Dai Q, Borcherding N, Wagner B, et al. Metadherin enhances vulnerability of cancer cells to ferroptosis. Cell Death Dis. 2019;10:682 pubmed publisher
Moerke C, Bleibaum F, Kunzendorf U, Krautwald S. Combined Knockout of RIPK3 and MLKL Reveals Unexpected Outcome in Tissue Injury and Inflammation. Front Cell Dev Biol. 2019;7:19 pubmed publisher

product information

brand :

Tocris

catalog number base :

6118

SKU :

6118/10

product name :

1S,3R-RSL3

units size :

10 mg (also 50 mg)

description :

Inhibits glutathione peroxidase (GPX4); induces ferroptosis

target :

Other Reductase Inhibitors

category :

Small Molecules

purity :

98%

observed molecular weight :

440.88

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

1S,3R-RSL3 is a glutathione peroxidase 4 (GPX4) inhibitor. Induces ferroptosis. Increases lipid peroxidase levels in vitro . Inhibits tumor formation and progression in vivo . . Negative control 1R,3R-RSL3 (Cat. No. 6687) also available.

top caption :

Inhibits glutathione peroxidase (GPX4); induces ferroptosis

extended description :

Inhibits glutathione peroxidase (GPX4); induces ferroptosis

chemical name text :

(1S,3R)-Methyl 2-(2-chloroacetyl)-2,3,4,9-tetrahydro-1-[4-(methoxycarbonyl)phenyl]-1H-pyrido[3,4-b]indole-3-carboxylate

formula :

C23H21ClN2O5

formula text :

C23H21ClN2O5

cas num :

1219810-16-8

USD :

282 USD

product details :

Inhibits glutathione peroxidase (GPX4); induces ferroptosis

storage :

Store at -20Â°C

more info or order :

Tocris Bioscience product webpage