PF 06273340 | Tocris Bioscience 6115 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

PF 06273340

catalog :

6115

quantity :

10 mg

price :

185 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

6115

SKU :

6115/10

product name :

PF 06273340

description :

Potent and selective pan-Trk inhibitor; peripherally restricted

target :

Trk Receptor Inhibitors

category :

Small Molecules

unit size :

10 mg

purity :

98%

observed molecular weight :

479.93

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent and selective pan-Trk inhibitor (IC50 values are 1, 2 and 6 nM for Trk C, B and A, respectively). Selective for Trk over a panel of ion channels, receptors and other enzymes. Peripherally restricted. Exhibits efficacy in a rodent model of inflammatory pain. Orally bioavailable.

catalog number base :

6115

product keywords :

PF06273340 Trk A B C tropomyosin-related kinase receptors neurotrophins inhibitors inhibits peripherally restricted potent selective Trk Receptors 6115,

extended description :

Potent and selective pan-Trk inhibitor; peripherally restricted

chemical name text :

N-[5-[[2-Amino-7-(2-hydroxy-1,1-dimethylethyl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]carbonyl]-3-pyridinyl]-5-chloro-2-pyridineacetamide

formula :

C 23 H 22 ClN 7 O 3

formula text :

C23H22ClN7O3

cas num :

1402438-74-7

2020 USD :

179

2021 USD :

185 USD

storage :

Store at RT

more info or order :

Tocris Bioscience product webpage