Zoledronic Acid | Tocris Bioscience 6111 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Zoledronic Acid

catalog :

6111

quantity :

10 mg (also 50 mg)

price :

70 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

6111

SKU :

6111/10

product name :

Zoledronic Acid

description :

Potent farnesyl diphosphate (FPP) synthase inhibitor

target :

Ras GTPase Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

272.09

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent bisphophonate farnesyl diphosphate (FPP) synthase inhibitor (IC50 = 20 nM). Inhibits osteoclast-mediated bone resorption. Also inhibits Ras signaling and tumor growth, and induces apoptosis in pancreatic cancer cells. Reverses epithelial-mesenchymal transition and inhibits breast cancer cell renewal via inactivation of NF- B.

catalog number base :

6111

product keywords :

bisphosphonate NF-KB NF-kappaB NF- B signaling inhibitors inhibits potent FPP synthase farnesyl diphosphate Ras Zometa Other Synthases/Synthetases NF-kB/IkB Cancer Stem Cells Ras GTPases 6111, Ras, GTP ase

extended description :

Potent farnesyl diphosphate (FPP) synthase inhibitor

chemical name text :

[1-Hydroxy-2-(1H-imidazol-1-yl)ethylidene]bisphosphonic acid

formula :

C 5 H 10 N 2 O 7 P 2

formula text :

C5H10N2O7P2

cas num :

118072-93-8

2020 USD :

2021 USD :

70 USD

alt names :

Zometa

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage