product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
Zoledronic Acid
catalog :
6111/10
quantity :
10 mg (also 50 mg)
price :
89 USD
more info or order :
Tocris Bioscience product webpage
citations: 1
Reference
Gobron B, Bouvard B, Legrand E, Chappard D, Mabilleau G. GLP-2 administration in ovariectomized mice enhances collagen maturity but did not improve bone strength. Bone Rep. 2020;12:100251 pubmed publisher
product information
brand :
Tocris
catalog number base :
6111
SKU :
6111/10
product name :
Zoledronic Acid
units size :
10 mg (also 50 mg)
description :
Potent farnesyl diphosphate (FPP) synthase inhibitor
target :
Ras GTPase Inhibitors
category :
Small Molecules
purity :
98%
observed molecular weight :
272.09
url print :
?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Zoledronic Acid is a potent bisphophonate farnesyl diphosphate (FPP) synthase inhibitor (IC50 = 20 nM). Inhibits osteoclast-mediated bone resorption. Also inhibits Ras signaling and tumor growth, and induces apoptosis in pancreatic cancer cells. Reverses epithelial-mesenchymal transition and inhibits breast cancer cell renewal via inactivation of NF- B.
top caption :
Potent farnesyl diphosphate (FPP) synthase inhibitor
extended description :
Potent farnesyl diphosphate (FPP) synthase inhibitor
chemical name text :
[1-Hydroxy-2-(1H-imidazol-1-yl)ethylidene]bisphosphonic acid
formula :
C5H10N2O7P2
formula text :
C5H10N2O7P2
cas num :
118072-93-8
USD :
89 USD
product details :
Potent farnesyl diphosphate (FPP) synthase inhibitor
alt names :
Zometa
storage :
Store at +4°C
more info or order :
Tocris Bioscience product webpage
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK