Lalistat 1 | Tocris Bioscience 6098 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Lalistat 1

catalog :

6098

quantity :

10 mg (also 50 mg)

price :

201 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Wu H, Ploeger J, Kamarajugadda S, Mashek D, Mashek M, Manivel J, et al. Evidence for a Novel Regulatory Interaction Involving Cyclin D1, Lipid Droplets, Lipolysis, and Cell Cycle Progression in Hepatocytes. Hepatol Commun. 2019;3:406-422 pubmed publisher

product information

brand :

Tocris

master code :

6098

SKU :

6098/10

product name :

Lalistat 1

description :

Potent and selective LAL inhibitor

target :

Lysosomal Acid Lipase Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

298.36

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent and selective lysosomal acid lipase (LAL) inhibitor (IC50 = 68 nM). Exhibits no significant activity against pancreatic lipase or lipoprotein lipase at 10 M concentration. Blocks LAL-mediated lipid hydrolysis of acetylated LDL and reduces efflux of cholesterol from lipid-loaded cells resulting in increased cellular cholesterol ester levels.

catalog number base :

6098

product keywords :

potent selective LAL inhibitors inhibits lysosomal acid lipase Neimann-Pick type c NPC storage cholesterol accumulation Lalistat1 Lysosomal Acid Lipase (LAL) 6098,

extended description :

Potent and selective LAL inhibitor

chemical name text :

4-(Piperidin-1-yl)-1,2,5-thiadiazol-3-yl morpholine-4-carboxylate

formula :

C 12 H 18 N 4 O 3 S

formula text :

C12H18N4O3S

cas num :

501104-16-1

2020 USD :

193

2021 USD :

201 USD

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage