Lalistat 1 | Tocris Bioscience 6098/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Lalistat 1

catalog :

6098/10

quantity :

10 mg (also 50 mg)

price :

234 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Wu H, Ploeger J, Kamarajugadda S, Mashek D, Mashek M, Manivel J, et al. Evidence for a Novel Regulatory Interaction Involving Cyclin D1, Lipid Droplets, Lipolysis, and Cell Cycle Progression in Hepatocytes. Hepatol Commun. 2019;3:406-422 pubmed publisher

product information

brand :

Tocris

master code :

6098

SKU :

6098/10

rank :

0.0006

product name :

Lalistat 1

description :

Potent and selective LAL inhibitor

target :

Lysosomal Acid Lipase Inhibitors

category :

Small Molecules

sizes available :

10 mg (also 50 mg)

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Lalistat 1 is a potent and selective lysosomal acid lipase (LAL) inhibitor (IC50 = 68 nM). Exhibits no significant activity against pancreatic lipase or lipoprotein lipase at 10 M concentration. Blocks LAL-mediated lipid hydrolysis of acetylated LDL and reduces efflux of cholesterol from lipid-loaded cells resulting in increased cellular cholesterol ester levels.

extended description :

Potent and selective LAL inhibitor

chemical name text :

4-(Piperidin-1-yl)-1,2,5-thiadiazol-3-yl morpholine-4-carboxylate

formula :

C 12 H 18 N 4 O 3 S

formula text :

C12H18N4O3S

cas num :

501104-16-1

USD :

234 USD

product details :

Potent and selective LAL inhibitor

storage :

Store the unopened product at 2 - 8 °C. Do not use past expiration date.

more info or order :

Tocris Bioscience product webpage