Nexinhib20 | Tocris Bioscience 6089/5 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Nexinhib20

catalog :

6089/5

quantity :

5 mg (also 25 mg)

price :

87 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

6089

SKU :

6089/5

rank :

0.06

product name :

Nexinhib20

description :

Rab27 inhibitor; inhibits neutrophil exocytosis; active in vivo

target :

Other Small Monomeric GTPase Inhibitors

category :

Small Molecules

sizes available :

5 mg (also 25 mg)

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Nexinhib20 is a Rab27 inhibitor (IC50 = 330 nM); inhibits Rab27a-JFC1 binding. Selectively inhibits neutrophil exocytosis, with no significant effect on other important innate immune responses including phagocytosis. Suppresses extracellular production of superoxide anion and cytochrome b plasma membrane expression. Also inhibits upregulation of adhesion molecules CD11b and CD66b. Displays in vivo anti-inflammatory activity.

extended description :

Rab27 inhibitor; inhibits neutrophil exocytosis; active in vivo

chemical name text :

4,4-Dimethyl-1-(3-nitrophenyl)-2-(1H-1,2,4-triazol-1-yl)-1-penten-3-one

formula :

C 15 H 16 N 4 O 3

formula text :

C15H16N4O3

cas num :

331949-35-0

USD :

87 USD

product details :

Rab27 inhibitor; inhibits neutrophil exocytosis; active in vivo

storage :

Store the unopened product at 2 - 8 °C. Do not use past expiration date.

more info or order :

Tocris Bioscience product webpage