PSB 12379 | Tocris Bioscience 6083/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

PSB 12379

catalog :

6083/10

quantity :

10 mg

price :

394 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Cser xe9 p C, Schwarcz A, P xf3 sfai B, L xe1 szl xf3 Z, Kellermayer A, K xf6 rnyei Z, et al. Microglial control of neuronal development via somatic purinergic junctions. Cell Rep. 2022;40:111369 pubmed publisher
Kang S, Hong S, Lee J, Peyton L, Baker M, Choi S, et al. Activation of Astrocytes in the Dorsomedial Striatum Facilitates Transition From Habitual to Goal-Directed Reward-Seeking Behavior. Biol Psychiatry. 2020;88:797-808 pubmed publisher

product information

brand :

Tocris

catalog number base :

6083

SKU :

6083/10

product name :

PSB 12379

units size :

10 mg

description :

Ecto-5 -nucleotidase (CD73) inhibitor

target :

Other ATPase Inhibitors

category :

Small Molecules

purity :

98%

observed molecular weight :

559.31

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

PSB 12379 is a selective high affinity ecto-5 -nucleotidase/CD73 inhibitor (Ki values are 2.21 and 9.03 nM at human and rat CD73, respectively). Blocks ecto-5 -nucleotidase-mediated adenosine production by preventing the conversion of AMP to adenosine. Exhibits selectivity over other ecto-nucleotidases and ADP-activated P2Y receptors tested.

top caption :

Ecto-5 -nucleotidase (CD73) inhibitor

extended description :

Ecto-5 -nucleotidase (CD73) inhibitor

chemical name text :

N6-Benzyl- , -methyleneadenosine 5 -diphosphate disodium salt

formula :

C18H21N5Na2O9P2

formula text :

C18H21N5Na2O9P2

USD :

394 USD

product details :

Ecto-5 -nucleotidase (CD73) inhibitor

storage :

Store at -20Â°C

more info or order :

Tocris Bioscience product webpage